I don’t know if men can or should, but I do. I bought a pair over the knee with 4 inch heels and find them very comfortable and easy to walk in. I’ve had a few stares and many smiles but nothing serious. I wear them over and under pant legs. I feel great wearing them. I’m very hetero and other than this, do not wear any other female attire and that’s probably too much for some people. Go for it guys if you like it!